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  • 小鼠抗RUNX1T1單克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW11938
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：20
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中文名稱(chēng): 小鼠抗RUNX1T1單克隆抗體

英文名稱(chēng): Anti-RUNX1T1 mouse monoclonal antibody

別    名: CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8

儲(chǔ)    存: 冷凍（-20℃） 避光

抗    原: RUNX1T1

宿    主: Mouse

反應(yīng)種屬: Human

相關(guān)類(lèi)別: 一抗

標(biāo) 記 物: Unconjugate

克隆類(lèi)型: mouse monoclonal

技術(shù)規(guī)格

Background:

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Applications:

WB, IF

Name of antibody:

RUNX1T1

Immunogen:

Fusion protein of human RUNX1T1

Full name:

runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3

Synonyms:

CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8

SwissProt:

Q06455

WB Predicted band size:

68 kDa

WB Positive control:

Hela, SVT2, A549, COS7, Jurkat, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000